Frequently Asked Questions

Yes, many insurance plans provide coverage. Coverage varies by plan, and our team will help verify your benefits and explain your options.

No. You cannot drive, operate machinery, or do anything that requires full alertness until the next day after a restful sleep. You must arrange for a trusted adult to drive you home.

Spravato is approved to be used with or without an oral antidepressant, depending on your treatment plan. Your provider will determine what is right for you.

The effectiveness of Spravato in preventing suicide or reducing suicidal thoughts has not been demonstrated. If you ever feel unsafe, call 988 or seek immediate help.

Treatment usually begins with an induction phase of twice-weekly visits for 4 weeks, followed by once-weekly sessions for weeks 5–8. After that, frequency is adjusted to once a week or once every two weeks, depending on your response. Your provider will reassess your progress regularly.

You will be monitored in the clinic for at least two hours after each session. Your provider will let you know when it is safe to leave.

The most common side effects include feeling disconnected (dissociation), dizziness, nausea, sleepiness, decreased sensitivity, anxiety, lack of energy, increased blood pressure, vomiting, and feeling drunk. These usually occur right after treatment and go away the same day.

Spravato may not be appropriate if you have certain medical conditions, such as an aneurysm, history of brain bleed, or uncontrolled high blood pressure. Your provider will review your medical history before beginning treatment.

Some patients notice improvement in symptoms within the first 24 hours, though results vary. It may take several weeks to fully assess your response.

Spravato contains esketamine, which has the potential for misuse or abuse. That is why it is only available through a certified clinic under supervision. Your provider will monitor you closely for safety.